Initially, the rash may look like a blood pimple or a blood blister that wont go away.
Over time, skin around the blister deteriorates, leaving an open wound.
The cause is unknown and difficult to diagnose because it resembles many other conditions.
Pichsakul Promrungsee / Getty Images
Medications and other treatments can relieve symptoms.
Pichsakul Promrungsee / Getty Images
How Does Pyoderma Gangrenosum Affect the Body?
Pyoderma gangrenosum leads to painful open wounds around the body.
At first, patients notice a small rash or blood blister.
Sometimes, these occur after minor scratches or skin injuries.
The affected area quickly expands, filling with dead cell matter called fibrinous debris.
The ulcers often have a blue or purple border.
They usually appear on the legs but can be anywhere, including the groin and genitals.
It usually occurs on the legs and trunk.It can lead to deep ulcers that are very painful.
This bang out makes up about 85% of pyoderma gangrenosum cases.
People with atypical pyoderma gangrenosum might not develop these ulcers.
These ulcers usually start with a small rash that spreads quickly.
The ulcers might continue spreading or heal on their own.
In addition to ulcers, other symptoms of pyoderma gangrenosum include:
Who Does Pyoderma Gangrenosum Affect?
Overall, it impacts about 1 in 100,000 Americans each year.
What Conditions Is Pyoderma Gangrenosum Associated With?
Pyoderma gangrenosum is closely associated with:
Is Pyoderma Gangrenosum Life-Threatening?
Pyoderma gangrenosum is a serious disease that can be life-threatening, especially if left untreated.
What Causes Pyoderma Gangrenosum?
Healthcare providers are still working to identify what causes pyoderma gangrenosum.
These cells respond to viruses, bacteria, and other pathogens to protect the body from infection.
How Is Pyoderma Gangrenosum Diagnosed?
There arent any specific tests for pyoderma gangrenosum.This can make it difficult to diagnose.
Pyoderma gangrenosum needs medical management, so when in doubt, see your primary care physician or a dermatologist.
Theres no specific treatment protocol for pyoderma gangrenosum.
Pyoderma gangrenosum is a chronic disease, and you may experience more ulcers in the future.
These doctors are knowledgeable about the skin, as well as the autoimmune conditions that can impact skin health.
Summary
Pyoderma gangrenosum (PG) is a chronic skin condition that can cause painful ulcers.
These ulcers usually occur on the legs and trunk but can develop anywhere.
Treatments include steroids, eczema drugs, and immunosuppressants.
Pain management and wound care are also important.
National Organization for Rare Diseases.Pyoderma gangrenosum.
George C, Deroide F, Rustin M.Pyoderma gangrenosum a guide to diagnosis and management.Clinical Medicine.
2023;15(6).
doi:10.7759/cureus.41181
American Osteopathic College of Dermatology.Pyoderma gangrenosum.
2020;9(12):686-694. doi: 10.1089/wound.2020.1168
DermNetNZ.Pyoderma gangrenosum.
