Disease-modifying antirheumatic drugs (DMARDs) are an example of medications that have been proven effective in treating RA.
Verywell / Mayya Agapova
What Are DMARDs?
Despite no definitive cure for RA, there is no lack ofoptions for treatment.
Verywell / Mayya Agapova
Currently there are multiple categories of DMARDs on the market.
They work to keep RA activity levels at their lowest possible levels within the body.
Some DMARDs can even put the disease into remission.
Most DMARDs have unique mechanisms and stop inflammation through a variety of ways.
Treatment guidelines consider DMARDs as the primary treatment option for RA.
Its brand names include Rasuvo, Otrexup, Trexall, and Rheumatrex.
It is FDA-approved for use in the treatment of RA and forms of lupus.
Hydroxychloroquine can be used alone or in combination with other DMARDs.
In most cases it seems to be as effective as methotrexate.
Just as each case of RA is different, so is every treatment plan.
For that reason, it is crucial to discuss your disease and its severity with your healthcare provider.
Your healthcare provider can determine how soon to start you on a DMARD.
Your physician’s clinical knowledge coupled with the latest treatment guidelines will determine the best fit for you.
For people with moderate-to-severe RA, methotrexate is usually the first-line treatment.
For people with low-to-moderate RA, hydroxychloroquine may be initiated first.
American College of Rheumatology.Rheumatoid arthritis.
Wasserman A.Rheumatoid arthritis: common questions about diagnosis and management.AFP.
2018;97(7):455-462.
2019;86(3):301-307. doi:10.1016/j.jbspin.2018.07.004
Johns Hopkins Arthritis Center.Rheumatoid arthritis treatment options.
American College of Rheumatology.Hydroxychloroquine(Plaquenil).
American College of Rheumatology.Sulfasalazine(Azulfidine).
