On the flip side, a negative result doesn’t necessarily mean that youdon’thave lupus.

What Is Lupus?

As with other autoimmune diseases, lupus is brought on by an immune system that has gone awry.

An illustration with information about “Does ANA-Negative Lupus Exist?"

Get our printable guide for your next doctor’s appointment to help you ask the right questions.

Lupus is called systemic because it attacks the body as a whole.

In their entirety, these findings can help support the diagnosis.

But not always, according to some experts.

Doctor Discussion Guide Woman

Get our printable guide for your next doctor’s appointment to help you ask the right questions.

What Is ANA-Negative Lupus?

Generally, anything under 1:80 is considered negative.

This is referred to as ANA-negative lupus.

Debating ANA-Negative Lupus

ANA-negative lupus is rare.

Some studies suggest that up to 2% of lupus cases are ANA-negative.

Get our printable guide for your next doctor’s appointment to help you ask the right questions.

National Institute of Arthritis and Musculoskeletal and Skin Diseases.Systemic lupus erythematosus (lupus).

Centers for Disease Control and Prevention.Lupus basics.

doi:10.1136/lupus-2014-000056

MedlinePlus.Antinuclear antibody panel.