The severity of this condition varies.
Types of Hypophosphatasia
The severity ofhypophosphatasiais closely tied to the age of onset of symptoms.
In addition, there are many individual differences when it comes to symptoms of this genetic disorder.
Verywell / Jessica Olah
Its features in one family member may not resemble those of another.
This enzyme, which removes oxygen and phosphorous from other molecules, is essential for mineralization.
It plays a critical role in ensuring necessary minerals are deposited into bones and teeth.
In turn, this inhibits mineralization.
That said, the outlook is improving.
Furthermore, families of those with the condition will inevitably also feel an impact.
While that road may be challenging, remember that its one not traveled alone.
Alongside dedicated specialists, you have the support of family and friends and a growing community of patients worldwide.
With advances in the understanding of HPP come advancements in its management.
On top of existing therapies for the condition are newer ones showing promise.
While theres still more work ahead, its important to remember how far weve come.
National Institutes of Health.Hypophosphatasia.
National Organization for Rare Disorders.Hypophosphatasia.
Shapiro J, Lewiecki E.Hypophosphatasia in adults: clinical assessment and treatment considerations.Journal of Bone and Mineral Research.
2018;88(6):356.e1-356.e11.
Harvard Health Publishing.10 steps for coping with a chronic condition.
