Learn more about hypogammaglobulinemia, including symptoms, causes, diagnosis, and treatment options.

What Are Immunoglobulins?

However, your symptoms may not show up until adulthood, typically during your 20s and 30s.

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Some complications may be serious, including:

What Is an Immunodeficiency Disorder?

Treatment

If you have secondary hypogammaglobulinemia, treating the underlying cause will help to reduce your symptoms.

Treatment for primary hypogammaglobulinemia typically involves antibiotics and/or immunoglobulin therapy.

Antibiotics can help to relieve the symptoms of frequent infections.

IVIG is also given in infusion clinics in outpatient centers set up to deliver this medication.

Usually, IVIG is monthly.

Subcutaneous Ig treatment (SCIg) is typically delivered at home and may require more frequent doses.

Low immunoglobulin levels reduce your bodys ability to fight off infection and prevent disease.

People with hypogammaglobulinemia frequently experience recurring respiratory and gastrointestinal infections.

Lung infections, sinus infections, and upper airway infections are especially common.

Hypogammaglobulinemia is diagnosed with blood tests that measure immunoglobulin levels.

Treatments usually involve antibiotics and immunoglobulin infusions to increase antibody levels over time.

If left untreated, you could experience severe medical complications.

Its important to talk to your healthcare provider as soon as possible about your treatment options.

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2019;52(10):e8926.

doi:10.1590/1414-431X20198926

National Cancer Institute.Immunoglobulin.

2022;149(5):1525-1560. doi:10.1016/j.jaci.2022.01.025

MedlinePlus.Immunoglobulins blood test.

A systematic review.Front Immunol.