Cholestatic pruritusis a symptom ofcholestatic liver disease.
It is a constant, severe, and sometimes debilitating itching sensation on various parts of the body.
Over 80% of people with cholestatic liver disease develop cholestatic pruritus.
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This article discusses the symptoms, causes, and treatment options for people with cholestatic pruritus.
However, there may be other, unknownpruritogensinvolved.
Pruritogens are substances that cause itching and the urge to scratch after they make their way into the skin.
When Cholestatic Liver Disease Is Left Untreated
If left untreated, cholestatic itching will worsen.
However, more severe consequences may occur, such as chronicliver failure.
Diagnosis
Diagnosing cholestatic pruritus is simple if a person has already been diagnosed with cholestatic liver disease.
Then they will develop a treatment plan for both the disease and symptoms like cholestatic pruritus.
Imaging of the liver and bile duct will be performed to look for functional issues or structural damage.
Other imaging tests may be used to get a better look if results come back inconclusive.
Treatment
Treatment for cholestatic pruritus can be challenging because there are various factors at play.
The first-line treatment for cholestatic pruritus is to treat the underlying condition, if possible.
For mild itching, simple skin care using lotions or emollients (moisturizers) may be enough.
They can include:
What Treatment Is Right for You?
No single treatment is right for everyone who deals with cholestatic pruritus.
To determine which one will work for you, talk to your healthcare provider about your options.
Coping
Coping with cholestatic pruritus can be difficult, if not debilitating.
In some cases, the itching can be so severe that it substantially affects your quality of life.
A person can even develop secondary depression or suicidal ideation as a result.
The best way to cope is to work with your healthcare provider to identify the best treatment option.
Summary
Cholestatic pruritus is characterized as an extreme and debilitating itching sensation sparked by cholestatic liver disease.
There are both noninvasive and invasive options available to you.
A Word From Verywell
Feeling itchy all the time can be frustrating and bothersome.
When you are so preoccupied by a severe itch, it can be hard to focus on anything else.
Talk to your healthcare provider about treatment options for both the disease and its symptoms.
Frequently Asked Questions
There are several viable treatment options available for liver disease-induced itching.
The first is medication.
Medications tend to work for most people with cholestatic itching.
However, other, more invasive options can be explored if medications do not work.
Roughly 80% to 100% of people with cholestatic liver disease will develop cholestatic itching.
In some cases, it is one of the most obvious symptoms of cholestatic liver disease.
Jaundice is also often present with cholestatic itching.
