Statins are widely used cholesterol-lowering drugs that can reduce the risk of major heart-related health problems.
Though statins generally have a good safety profile, they can cause side effects in some people.
Still, healthcare providers believe that the benefits of statins outweigh the risks related to side effects.
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There are options for managing side effects if they become bothersome.
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What Are Statins?
Statin medications are used with diet and exercise to treathypercholesteremia(high blood cholesterol levels).
Statins belong to the prescription drug class called hydroxymethylglutaryl-coenzyme A (HMG CoA) reductase enzyme inhibitors.
They work to reduce the production of cholesterol in the liver.
They also increase the concentration ofhigh-density lipoprotein (HDL), also known as good cholesterol.
However, they can cause some side effects.
In most cases, they are reversible but sometimes require stopping therapy for a while.
However, these are generally uncommon.
Healthcare providers believe that statins' benefits outweigh the risks of these side effects.
Muscle Pain and Soreness
Some people reportmild muscle painand soreness while taking statins.
If the side effects become especially bothersome, your healthcare provider might reduce the dose.
However, they are not recommended in certain cases.
Some people are at an increased risk of side effects.
Avoid drinking large amounts of grapefruit juice while taking statins.
However, an 8-ounce (240-milliliter) glass of juice or one grapefruit can be safely consumed.
Summary
Statins are a widely used group of drugs that are generally well tolerated.
Like any other key in of drug, they may cause a few side effects in some people.
Tell your healthcare provider about any other drugs you take before taking statins.
Hussain A, Kaler J, Ray SD.The benefits outweigh the risks of treating hypercholesterolemia: the statin dilemma.Cureus.
15(1):e33648.
U.S. Food and Drug Administration.Statins.
MedlinePlus.How to take statins.
U.S. Food and Drug Administration.Cholesterol-lowering drugs gets labeling changes.
Hu M, Cheung BMY, Tomlinson B.Safety of statins: an update.Ther Adv Drug Saf.
2022;400(10355):832-845. doi:10.1016/S0140-6736(22)01545-8.
Pergolizzi JV Jr, Coluzzi F, Colucci RD, et al.Statins and muscle pain.Expert Rev Clin Pharmacol.
2021;13:211-219. doi:10.2147/DHPS.S333738.
Centers for Disease Control and Prevention.Signs and symptoms of rhabdomyolsis.
Ramkumar S, Raghunath A, Raghunath S.Statin therapy: review of safety and potential side effects.Acta Cardiol Sin.
2022;191(2):719-725. doi:10.1007/s11845-021-02651-x
