Sometimes thesefeverscome with other symptoms, but not always.
These conditions are rarely fatal but may result in lifelong challenges and treatments.
Keep reading to learn more about the different types of periodic fever syndromes and how to manage them.
Illustration by Theresa Chiechi for Verywell Health
Most of these conditions are hereditary, passed down through families as ageneticmutation.
The most common periodic fever syndromes are listed below.
Autoinflammatory diseases represent a sort of malfunction within the immune system.
This can result in a number of symptoms, including fevers.
In others, inflammation is more widespread, causing damage to other organs.
These diseases usually appear in infancy or childhood but can continue into adulthood, too.
Typically, the diagnosis will rely on family histories and the presence of certain symptoms.
Biologics are frequently used to manage autoimmune and auto-inflammatory disorders.
In PFAPA and HIDS, symptoms typically lessen throughout childhood, especially after age 10.
Mild symptoms may continue into adulthood or contribute to other conditions like arthritis.
Mild symptoms may continue into adulthood or contribute to other conditions like arthritis.
FMF is a lifelong condition that is manageable as long as colchicine treatment is continuous.
NOMID, on the other hand, often results in serious physical deformities and/or neurological damage.
Many of these conditions, particularly Muckle-Wells, are also associated with a condition called amyloidosis.
These disorders are largely rare and are not contagious.
Most of these conditions are passed through families as a genetic mutation.
Symptoms can stick around for life, but anti-inflammatory medicines and new biologic treatments can help manage them.
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