An HIV rash generally refers to a skin reaction that shows up when you are initially infected with HIV.

Certainmedications used to treat HIVcan also cause skin eruptions.

Acute Seroconversion Rash

This photo contains content that some people may find graphic or disturbing.

Person with HIV Rash

U.S. National Library of Medicine / National Institutes of Health

Even so, viruses circulating in the blood will continue to progressively deplete the immune system.

One rash that commonly occurs during this stage is called apruritic popular eruption(PPE) of HIV.

This small, itchy rash is often the only sign of HIV in an otherwiseasymptomaticperson.

Skin broken out in red rash

Suvit Maka / Getty Images

Women are affected more than men, as are people who live in tropical climates.

Symptoms of PPE include:

Topical steroidsandoral antihistaminesmay help control symptoms.

People not yet placed on antiretroviral therapy should be started immediately.

Hot tub folliculitis

Joel Carillet / Getty Images

These immune defenders help the body fight fungal or parasitic infections.

In people without HIV, the condition is known asOfujidisease.

Seborrheic Dermatitis

Reproduced with permission from DermNet New Zealandwww.dermnetnz.org2023.

A close up of seborrheic dermatitis (eczema) on the scalp

Reproduced with permission from © DermNet New Zealandwww.dermnetnz.org2023.

The degree of immune impairment is measured by a blood test called aCD4 count.

At this stage, a person is said to beimmunocompromisedand to haveAIDS.

The rash tends to appear one to two weeks after the start of treatment.

Shingles.jpg used under a Creative Commons license at http://commons.wikimedia.org/wiki/File:Herpes_zoster_chest.png

Shingles (herpes zoster) of the chest.Fisle / Creative Commons license

Some have been known to develop within one to two days.

Antihistamines may be prescribed to reduce redness, itching, and swelling.

Both SJS and TEN trigger the widespread blistering and shedding of skin.

A person experiencing a drug hypersensitivity reaction

U.S. National Library of Medicine

When to See a Healthcare Provider

You should discuss any rash with your healthcare provider.

They may be able to provide treatments or recommend a medication change that can help resolve your symptoms.

It can also be because of a hypersensitivity reaction to medications used to treat HIV or HIV-related infections.

Steven-Johnson Syndrome

U.S. National Library of Medicine / National Institutes of Health

Depending on the cause, the rash may be managed with steroids, antibiotics, or antihistamines.

If the rash is the result of a drug reaction, HIV treatment is almost invariably stopped.

Cowan EA, McGowen JP, Fine SM, et al.Box 1: acute retroviral syndrome (a).

2022;194(45):E1541.

doi:10.1503/cmaj.220656

National Institutes of Health.The stages of HIV infection.

2021;49(4):799-801. doi:10.1007/s15010-020-01543-z

Motswaledi HM.Common dermatological conditions in the HIV patient.S Afr Fam Pract.

2019;6(sup1):S19-S24.

doi:10.1080/20786190.2019.1610234

Siripurapu R, Ota Y.Human immunodeficiency virus: opportunistic infections and beyond.Neuroimag Clin N Am.

2019;19(4):272-282. doi:10.1097/ACI.0000000000000545

National Library of Medicine.Stevens-Johnson syndrome/toxic epidermal necrolysis.

National Library of Medicine.Anaphylaxis.