Serums are easy to apply, requiring only a few swipes of a wand per day.

Searches for the best lash serum have racked up more than 1.5 billion views on TikTok.

Although lash serums are on the up and up, theyre not without risk.

eye mask with the depiction of eyelashes

Iryna Veklich / Getty Images

What Is an Eyelash Growth Serum?

PGAs can cause periorbital volume loss, which Sartor describes as the melting of fat around your eyes.

What are Prostaglandin Analogs (PGAs)?

PGAsare compounds that were initially manufactured to treat an eye condition called glaucoma.

No controlled clinical trials exist to assess their frequency and prevalence.

Sartor said any of these potential side effects depend on what a persons eye looked like before using serums.

It can lead to many individuals to appear more tired with darker under-eye circles, she said.

Which Eyelash Serums Contain PGAs?

Eyelash serums that contain PGAs are available over the counter as well as via prescription, Sartor said.

Eyelash serums that donotcontain PGAs can still have potential health risks.

Should You Stop Using Eyelash Growth Serums?

This can result in appearance changes in and around the eye.

The good news is these changes are usually reversible once you stop using the serum.

2022;42(11):1241-1249. doi:10.1093/asj/sjac156