Alternate Name for Chronic Fatigue Syndrome

SEID stands for systemic exertion intolerance disease.

SEID was previously known aschronic fatigue syndrome.

From Chronic Fatigue Syndrome to SEID

SEID means systemic exertion intolerance disease.

Out-of-breath woman with her hands on her knees

Hinterhaus Productions / Getty Images

When something is systemic, it affects the entire body.

“Exertion intolerance” refers to the hallmark symptom of SEID, calledpost-exertional malaise.

Until 2015, SEID was known as chronic fatigue syndrome (CFS).

It’s important to note that chronic fatigue syndrome has not been officially renamed as systemic exertion intolerance.

The term “myalgic encephalomyelitis”/chronic fatigue syndrome is most commonly used in medical literature and clinical practice.

What is Myalgic Encephalomyelitis?

You may also see SEID referred to as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

What Causes SEID?

While the exact cause or causes of SEID are unknown, a few possible causes have been identified.

Increasing research shows that SEID usually begins following an infection.

In fact, up to 80% of people with SEID develop the disease following a viral illness.

Twin studies have shown show higher rates of SEID in identical, rather than fraternal, twins.

More specific genetic causes have not been identified.

Summary

SEID stands for systemic exertion intolerance disease.

SEID was previously known as chronic fatigue syndrome or myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

The Lancet.What’s in a name?

Systemic exertion intolerance disease.The Lancet.

2016;6(1):10. doi:10.3390/diagnostics6010010

Mount Sinai.Chronic fatigue syndrome.

2024 Jun;15(1).

doi:10.3389/fimmu.2024.1386607

Centers for Disease Control and Prevention.Clinical overview of ME/CFS.

National Academies Press (US); 2015 Feb.