Rituximab triggers an immune response from the patient against CD20-positive cells.
Cyclophosphamideis known as an alkylating agent, and it has both anti-cancer and anti-immune activity.
Oncovinor vincristine binds to little structures in cells called microtubules and interferes with the cells' ability to divide.
Prednisoneis a steroid agent with anti-inflammatory properties, and it has many different uses in medicine.
In certain sensitive cancer cell types, prednisone can stimulate programmed cell death.
R-CHOP is widely used in non-Hodgkin lymphoma.
How Often Is Each Agent Given?
As an example of some of the emerging variations on R-CHOP, something called R-mini-CHOP is being explored.
2016;95(38):e4893.
doi:10.1097/MD.0000000000004893
National Comprehensive Cancer internet.NCCN Guidelines for Patients: Follicular Lymphoma.
Fort Washington, PA: NCCN; 2019.
2018;5(6):e507.
