Serious side effects could include vision changes, shortness of breath, and jaundice.

These side effects include:

Does Provera Cause Weight Changes?

Both weight gain and weight loss are listed as possible side effects of Provera.

Marking missed period on calendar

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Serious Side Effects

Other, less common side effects may be more serious.

Provera isn’t safe for everyone.

After taking Provera, your period will become more regular.

Some people experience lighter periods than usual when taking this medication.

Taking Provera may also significantly reduce or stop bleeding.

Provera is used to regulate periods and can also be used to delay periods.

Does Provera Clean You Out?

Provera mimics progesterone, which helps regulate your menstrual cycle and thin your uterine lining.

Taking Provera can significantly reduce or stop menstrual bleeding.

Do not take more or less of this medication than instructed.

The dosage used varies by the condition being treated.

Modifications

If you have significant liver impairment fromalcoholiccirrhosis, Provera is discouraged.

If it is prescribed, your dosage may be lower than the standard dose.

Dosages may not be established for off-label uses.

Always follow your healthcare provider’s instructions for prescription medications.

Provera must be taken at certain times, so follow all instructions carefully.

Warnings and Interactions

Provera by itself is not a contraceptive and won’t prevent pregnancy.

Use another form of birth control, such as a condom, while you’re taking this drug.

You may not be able to take Provera while also using hormonal birth control.

Other drugs may pose problems as well.

Be sure your healthcare provider knows everything you’re taking, including over-the-counter drugs and nutritional supplements.

Using the same pharmacy for all of your prescription medications can help you avoid negative drug interactions.

Tell your healthcare provider about all medications, supplements, and vitamins you are currently taking.

Summary

Provera is a prescription medication that can help regulate your menstrual cycle.

It has both common and serious side effects, ranging from headaches to heart problems.

It is typically taken for five to 10 days at a specific time during your menstrual cycle.

Most people will have a period between three and seven days after they finish a course of treatment.

Provera is prescribed to treat irregular menstruation and conditions like PCOS and endometrial hyperplasia.

It also may be used to treat other diseases, such as endometrial cancer.

If taking Provera, do so as directed and watch for any symptoms or side effects.

Prescribers' Digital Reference: PDR.Provera.

American Cancer Society.Hormone therapy for endometrial cancer.

Food and Drug Administration.Menopause: Medicines to help you.

NHS.Common questions about medroxyprogesterone tablets.

2022;28:e936727.

doi:10.12659/MSM.936727

Cancer Research UK.Medroxyprogesterone acetate (Provera).

Pfizer.PROVERA Warnings and Precautions.

Food and Drug Administration: FDA AccessData.Provera (medroxyprogesterone acetate tablets, USP).