Reported reactions have includedurticaria, asthma, and, rarely,anaphylaxis.

They are generally very safe, with few side effects.

There is no FDA-approved blood or skin test to help rule in or out a diagnosis of PPI allergy.

Woman looking at medication

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Hypersensitivity Reactions to Proton Pump Inhibitors.

Curr Opin Allergy Clin Immunol.