However, they differ in how they work, their duration of use, and their side effects.

Famotidine works faster but omeprazole is more effective and lasts longer.

Omeprazoleis used to treat similar conditions, in addition toHelicobacter pylori(H. pylori) infections.

Omeprazole

Clubfoto / Getty Images

Clubfoto / Getty Images

What Is Famotidine?

Brand-name versions include Pepcid, Pepcid AC, and Zantac 360.

It’s also used in adults to:

How Does Famotidine Work?

Taking famotidine 15 to 60 minutes before eating or drinking can help prevent or lessen heartburn symptoms.

Famotidine starts working within one hour, and its effects last about 12 hours.

What Is Omeprazole?

Omeprazole is a generic medication that belongs to a class of drugs calledproton pump inhibitors (PPIs).

Omeprazole is available in prescription and nonprescription (OTC) strengths.

It is typically taken once daily for 14 days.

You shouldnt take it for more than 14 days unless advised to do so by your healthcare provider.

How Does Omeprazole Work?

Omeprazole works by inhibiting the pumping of gastric acid and blocking the final step in acid production.

Omeprazole is not an antacid, and it does not provide instant relief fromheartburn symptoms.

It can take one to four days of treatment before omeprazole reaches its full effect.

However, some people will notice some relief of heartburn symptoms within the first 24 hours.

It usually keeps working to decrease stomach acid production for about a day.

How Do the Dosages Compare for Famotidine vs. Omeprazole?

Famotidine and omeprazole have different recommended dosages.

Be sure to take the dosage your provider recommends.

The dosages vary depending on the childs age, weight, and condition.

Your childs healthcare provider will recommend or prescribe the dosage that suits your childs needs.

It is safe to use both since they work differently in the body.

Taking both can provide an additive effect to reduce reflux symptoms.

The following table is not all-inclusive; other side effects may occur.

Interactions for Famotidine vs. Omeprazole

Drug interactions are possible with famotidine and omeprazole.

This section describes some of the most important interactions to be aware of, but others may occur.

Your provider can ensure they are safe to take together.

What Are Other Ways To Help Manage GERD?

Some people can manage GERD symptoms by makinglifestyle changes.

For best results, continue to follow lifestyle and dietary changes while taking medications for GERD.

Summary

Famotidine and omeprazole treat similar conditions but work in different ways to reduce stomach acid.

These drugs are available in OTC and prescription strengths.

Speak with your healthcare provider if you have questions about whether famotidine or omeprazole may be right for you.

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