Although there are several causes of NGU, the most common ischlamydia, another sexually transmitted infection.
Often, cases of NGU go undiagnosed and people receive the sametreatment for chlamydia.
That is often because the infection is brought on by a fungal or parasitic infection, such as trichomoniasis.
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(Sometimes the parasitic infection is in addition to a bacterial infection!)
Therefore, if the initial treatment fails, healthcare providers will try other options.
(Often NGU is caused bymycoplasma, but that is only rarely tested for.)
This is because some of the bacteria that cause urethritis can be difficult to identify.
Therefore, treating NGU this way is an effective way to eliminate the most common suspects.
The moxifloxacin, in particular, is a relatively new recommendation.
In contrast, metronidazole and tinidazole are used to treat possible trichomoniasis infections.
Additional Treatment Notes
You should generally stop having sex while on treatment.
This reduces the likelihood that you and your partner willpass an infection back and forth.
Any regular sexual partner should also be referred for testing and treatment when you are diagnosed with anSTD.
National Health System.Non-gonococcal urethritis.
Cleveland Clinic.Nongonococcal urethritis in men.
U.S. Centers for Disease Control and Prevention.Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR.
Brill JR.Diagnosis and treatment of urethritis in men.Am Fam Physician.2010;81(7):873-878.
Moi H, Blee K, Horner PJ.Management of non-gonococcal urethritis.BMC Infect Dis.
2015;15:294. doi:10.1186/s12879-015-1043-4
Bradshaw CS, Jensen JS, Waites KB.New horizons in mycoplasma genitalium treatment.J Infect Dis.
2017;216:S412-S419.
