Niacinflush may occur after taking large supplemental doses of niacin (vitamin B3).

Niacin helps to metabolize food for energy and is important for cellular function.

This supplement is often used to treat high cholesterol levels.

A person holds a niacin tablet to take with a glass of water

Alexandr Kolesnikov / Getty Images

While uncomfortable, the resulting warm, itchy, red skin is not dangerous.

That means some supplement products may not contain what the label says.

Capillaries are the smallest blood vessels that form a connection between the smallest arteries with the smallest veins.

This expansion increases blood flow to the surface of the skin.

Instead, the affected area may be discolored or darker than the rest of the skin.

Should You Worry?

Niacin flush is not harmful, though it may be unpleasant.

It generally lasts just a short time.

Stop taking high-dose niacin supplements if you are pregnant, and discuss appropriate supplements with a healthcare provider.

How Much Niacin Causes Flushing?

Flushing usually occurs after taking 30 to 50 milligrams (mg) or more of nicotinic acid.

Niacin supplements are often prescribed to treatdyslipidemia(too high or low cholesterol levels).

However,statinshave become the standard medication used to treat high cholesterol levels.

Supplemental niacin may also reduce blood pressure,support brain health,and improve skin health.

Very high supplemental doses of niacin of 1,000 to 3,000 or more can cause more serious side effects.

Most notably,livertoxicity is common with very high doses of niacin.

If you experience these symptoms, contact a healthcare provider for guidance.

Supplement Guidance to Minimize Skin Flushing

Experts have found some strategies to help minimize skin flushing.

These include:

Summary

Niacin flush occurs after taking high doses of supplemental niacin.

Symptoms include red, itchy skin around the face, neck, and upper chest.

Niacin flush may be uncomfortable but is harmless and generally lasts 30 to 90 minutes.

Niacin supplements are often used to treat high cholesterol levels.

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Office of Dietary Supplements.Niacin fact sheet for health professionals.

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Campbell JM.Supplementation with NAD+ and Its precursors to prevent cognitive decline across disease contexts.Nutrients.