Many Americans risk developing digestive disorders due to unhealthy eating or lifestyle practices, such asexcessive alcohol consumptionorsmoking.
Among these risks is a digestive disorder calledgastroesophageal reflux disease (GERD).
Two treatment options are Nexium (esomeprazole) and Prilosec (omeprazole).
Bloomberg / Getty Images
Bloomberg / Getty Images
What Is Nexium?
Nexium, containing the active ingredient esomeprazole, is an orally administered PPI that decreases acid in the stomach.
Nexium is available by prescription and as an over-the-counter (OTC) medication.
PPIs work by decreasing the amount of acid your stomach makes.
This is called off-label prescribing.
Nexium works by decreasing the amount of acid your stomach makes.
Nexium is administered in various ways, including tablets, capsules, and granules.
What Is Prilosec?
Prilosec, containing the active ingredient omeprazole, is a PPI.
Like Nexium, it works by decreasing acid in the stomach.
Prilosec is available both OTC and by prescription.
Prescription Prilosec is dispensed in pharmacies primarily as generic omeprazole, as many brand-name forms are no longer available.
Prilosec works by decreasing the amount of acid made by your stomach.
It is available in tablets, capsules, and orally disintegrating tablets.
Pharmacies commonly dispense prescription omeprazole for adults as generic omeprazole capsules.
Dosage Comparison
The following offers general dosing guidelines for Nexium vs. Prilosec.
Moreover, dosing may differ based on the drug’s mode of administration.
Always talk with a healthcare provider before using Nexium or Prilosec.
These drugs are chemically very similar and act similarly on the body.
Regarding efficacy, some studies found that Nexium may be more effective than Prilosec.
One study found Nexium significantly more effective than omeprazole in people with GERD and erosive esophagitis.
It’s important to note that either Nexium or omeprazole can be effective.
Always consult your healthcare provider for personalized medical advice.
Call 911 if your symptoms feel life-threatening or if you think you have a medical emergency.
Precautions
PPIs, like Nexium or Prilosec, are not appropriate for everyone.
Other people who should not take Nexium or Prilosec include individuals taking Edurant (rilpivirine) medication.
While taking Nexium or Prilosec, do not start any new medications without approval from your healthcare provider.
Some drug interactions include:
This is not a complete list of drug interactions.
Other drug interactions may occur with Nexium or Prilosec.
Consult your healthcare provider for more information about drug interactions and how they may affect you.
What Are Other Ways to Help Manage GERD?
Summary
GERD is agastrointestinal (GI) disorderthat affects around 20% of adults in North America.
you might always consult your healthcare provider for these two medications.
Keep away from direct light, heat, and moisture.
Do not store it in the bathroom.
Keep out of reach and out of sight of children and pets.
The cost of the prescription formulations depends on your insurance plan.
However, the price should be reasonable since both medications have generic forms.
The price will vary by medicine, dosage, quantity, pharmacy, and insurance plan.
you’ve got the option to ask your insurance provider for up-to-date coverage and co-pay information.
OTC Nexium and Prilosec are also reasonably priced, especially when you choose the generic version.
Some studies have found that long-term use of a PPI can increase the risk of gastric cancer.
As always, consult your healthcare provider for medical advice.
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