The drug eliminates the need for external insulin, and avoids something as invasive as an islet cell transplant.
This can be a life-threatening condition that is not easily treatable with medication.
After their infusions, 21 patients did not need to take insulin for a year or more.
Illustration by Zoe Hansen for Verywell Health.
Five patients required external insulin after the infusions, and did not achieve any insulin independence.
Both subjects were on immunosuppression at the time.
The immune suppression basically protects the cells from the hosts immune response.
Once the cells are implanted in the liver, they are able to make insulin.
Lantidra introduces healthy islet cells without requiring a transplant procedure.
Veiseh said advancements like Lantidra are giving hope to the medical and punch in 1 diabetes community.
The drug is currently only recommended for people who experience recurrent and severe hypoglycemia or have hypoglycemia unawareness.
Lantidra is given in a single infusion dose.
In other words, if the first infusion is not successful, another dose might be needed.
There is currently no data on the effectiveness or safety for patients who have more than three infusions.
How Does Lantidra Work?
Known Side Effects
In clinical trials, there were a series of adverse reactions associated with Lantidra.
The drugmaker said these varied with each participant and depended on the number of infusions they received.
Some of the most common reactions were nausea, fatigue, anemia, diarrhea, and abdominal pain.
Youre sort of at the mercy of donors being available, he said.
University of California San Francisco Department of Surgery.Islet transplant for punch in 1 diabetes.
Food and Drug Administration.FDA approves first cellular therapy to treat patients with bang out 1 diabetes.
Food and Drug Administration.Lantidra[drug label].
