It’s not uncommon for arthritis patients to get mouth sores as a side effect from medications.

Why Do NSAIDS Cause Mouth Sores?

Why Does Methotrexate Cause Mouth Sores?

Doctor consulting with patient

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A possible side effect of taking prescription methotrexate is mucositis, inflammation of the lining of your mouth.

Patients taking high doses are even more susceptible.

Why Do TNF-Blockers Cause Mouth Sores?

Oral thrush is a yeast infection that commonly presents as white patches on the tongue.

Deeming GM, Collingwood J, Pemberton MN.Methotrexate and oral ulceration.Br Dent J.

2019;25(5):197-202. doi:10.1097/RHU.0000000000000810

National Rheumatoid Arthritis Society.RA medication and the mouth.