Meloxicam’s risk of gastrointestinal (GI)-related side effects is lower than naproxen.

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What Is Meloxicam?

Meloxicam is an NSAID used to relieve various types of pain.

Person spilling pills out in the palm of their hand from a pill bottle

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How Does It Work?

Meloxicam inhibits COX-1 and COX-2, the enzymes that produceprostaglandins.

Meloxicam preferentially inhibits COX-2 over COX-1 at low doses, such as 7.5 milligrams (mg).

What Is Naproxen?

Naproxen is also an NSAID, and it is approved for prescription and OTC use.

They will not work fast enough to treat acute pain (sudden or urgent).

Naproxen is a nonselective inhibitor of COX-1 and COX-2.

It works by reducing prostaglandin synthesis.

Meloxicam vs. Naproxen: Which Is Stronger?

Meloxicam and naproxen are both effective pain relievers.

It was also better tolerated, with a significantly lower incidence of Gl and kidney side effects.

Consult your healthcare provider to determine the most suitable option for you.

How to Take Meloxicam and Naproxen

Can You Take Meloxicam and Naproxen Together?

NSAIDs can cause serious side effects, including heart-related (cardiovascular) risks and GI bleeding.

Cardiovascular Risks

Taking meloxicam or naproxen may increase the risk of heart attack or stroke.

These events can occur at any time during use.

NSAIDs and some other medicines can interact with each other and cause serious side effects.

Do not start taking new medications without talking to your healthcare provider first.

Who Shouldnt Take Meloxicam or Naproxen?

Meloxicam is considered more potent and longer lasting, requiring lower dosages and less frequent administration.

Meloxicam is also a selective COX-2 inhibitor, reducing the risk of GI side effects compared to naproxen.

However, NSAIDs that are selective COX-2 inhibitors, like meloxicam, have increased cardiovascular risk.

NSAIDs like naproxen may be preferred in people with low to moderate GI risk and high cardiovascular risk.

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