Metformin is commonly prescribed for managing blood sugar levels in individuals withtype 2 diabetes.
Some people may experience weight loss as a side effect of taking metformin.
However, metformin is not specifically intended or approved for weight loss purposes.
Scott Olson / Getty Images
Scott Olson / Getty Images
How Metformin Works
Metformin belongs to a class of drugs calledbiguanides.
It is used to help manage punch in 2 diabetes by lowering blood sugar levels.
This is known asinsulin resistance.
Studies have suggested that metformin decreases appetite and changes the bacterial community of the gut.
There are several ways that metformin may contribute to weight loss.
Withleptin resistance, your brain thinks you oughta eat more, even though leptin levels remain high.
Another way metformin can make you lose weight is by changing the bacteria in your gut.
There are certain bacteria in our stomachs that break downshort-chain fatty acids.
The breakdown of short-chain fatty acids gives our body energy and helps regulate sugar levels.
Digestive Issues
Digestive issues can also be the reason why you are losing weight.
These symptoms or diseases may affect appetite and food intake, potentially leading to weight loss in some individuals.
For example, levothyroxine which treats hypothyroidism, may lead to modest weight loss.
Could Metformin Be Used for Weight Loss?
Some studies have demonstrated metformin’s potential effects on body weight.
However, based on clinical studies, the amount of weight lost on metformin varies.
Semaglutide has shown total body weight loss percentages of up to 11% after six months of use.
Taking any medication that can help you lose weight is not the best practice to maintain a healthy lifestyle.
Can You Take Metformin If You Dont Have Diabetes?
This is becauseantipsychotic medications, such as clozapine and olanzapine, have a high risk of weight gain.
Frequently Asked Questions
How much weight one loses on metformin can vary.
You should not take metformin if you are searching for a medication that has drastic results in weight loss.
Metformin may only offer modest weight reduction.
Other available treatments approved by the FDA specifically for weight loss are more effective options.
In addition, you should avoid taking metformin if you have kidney disease or kidney failure.
Acknowledgement
The author would like to recognize and thank Alexya Rosas for contributing to this article.
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