That means almost three-quarters of the relatives had physical signs of susceptibility or early symptoms.
Additionally, pain sensitivities of blood relatives were significantly higher than those of people in the control groups.
A genetic susceptibility isn’t the same as a hereditary disease.
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In true genetic diseases, inheriting the gene(s) means you have or will develop the disease.
If those conditions are never met, youll probably never have fibromyalgia.
Some research suggests that about 50% of your susceptibility to fibromyalgia comes from genetic factors.
Associated Genes
Multiple genes have been targeted by researchers for their possible involvement in fibromyalgia.
A 2020 study found abnormalities in more than 220 microRNAs and in the expression of nearly 150 genes.
Many of the abnormalities were linked to musculoskeletal disease, immune-system disease, and mental disorders.
This system deals with homeostasis.
These conditions and several others fall under the umbrella termcentral sensitivity syndromes (CSS).
No one is sure, but it comes off as a combination of genetics and other factors.
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