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They may be used to deliverchemotherapy drugslike Doxil (doxorubicin) directly into a joint affected by cancer.
When used for alleviating pain, different intra-articular therapies work in different ways.
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Intra-articular treatments are most commonly used to treatosteoarthritis, acutegout, andrheumatoid arthritisof the knee.
Long-term use of corticosteroids has been thought to progressively damage the joints, but this is controversial.
Corticosteroid shots are typically administered no less than three months apart.
The duration of relief can vary based on the key in of steroid used.
Hyaluronic Acid
Hyaluronic acid is a naturally occurring substance found in synovial fluids that lubricate the joints.
With osteoarthritis, this substance can rapidly break down and lead to a worsening of the condition.
Intra-articular injections have been used to increase lubrication, reduce pain, and improve therange of motionin a joint.
However, clinical studies have been mixed on how effective these shots really are.
The American College of Rheumatology strongly recommends against the use of PRP in knee and hip osteoarthritis.
Side Effects
The two main side effects associated with intra-articular injections are infections and local site reactions.
Other side effects can occur in relation to the specific drugs or substances injected.
Corticosteroid injects were found to have minimal systemic effects.
Botox
Intra-articular Botox injections have very few side effects.
Injection site reactions are the most common side effect and may include redness or bruising.
Allergic reactions to botox, though rare, are possible and can include anaphylaxis.
Side effects typically resolve within 48 hours.
Frequently Asked Questions
Intra-articular injections are given directly into the joint.
Intra-articular injections can be painful.
Pain from an intra-articular injection occurs during the procedure and may linger for a few hours after treatment.
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