Hyaline casts result from a specific protein called “uromodulin.”

Sometimes, hyaline casts result from dehydration or strenuous exercise and do not require further testing.

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Why Are Hyaline Casts in Urine?

A gloved hand holding a urine sample

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However, hyaline casts are slightly different because they do not always indicate kidney disease.

Generally, zero to two hyaline casts in LPF are not cause for concern.

High Range of Hyaline Casts

Generally, casts are indicative of possible kidney disease.

Causes of Hyaline Casts in Urine

Illustration by Joules Garcia for Verywell Health

Interpreting Results: What Do High Hyaline Casts Mean?

Hyaline casts can be seen in a microscopic urinalysis test.

Generally, a normal amount of hyaline casts is 02/LPF.

Testing might include:

Summary

Hyaline casts are a specific jot down of sediment found in urine.

Often, urinary casts can help identify kidney disease processes.

Hyaline casts, however, do not always indicate a kidney disease process.

If the hyaline cast count is greater than two/LPF, it could indicate kidney or heart disease.

For such cases, a healthcare provider will likely order additional testing.

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LabCE.Formation and significance of casts.

https://doi.org/10.1038/nrneph.2017.101/

National Library of Medicine.Urinalysis.

Osmosis from Elsevier.Hyaline casts: what are they, causes, diagnosis, treatment, and more.

National Institute of Diabetes and Digestive and Kidney Diseases.Glomerular disease.

National Institute of Diabetes and Digestive and Kidney Diseases.Pyelonephritis.