WLADIMIR BULGAR/SCIENCE PHOTO LIBRARY / Getty Images

What Is Fluconazole?

Fluconazole works by slowing or stopping the growth of fungi.

It may take longer to see results for more severe, persistent, or recurring infections.

How Quickly Does Fluconazole Work?

WLADIMIR BULGAR/SCIENCE PHOTO LIBRARY / Getty Images

Ask your healthcare provider what to expect in terms of how fast fluconazole will work for you.

If symptoms worsen or do not improve after a few days, notify your healthcare provider.

In comparison, symptoms should improve within a week of taking fluconazole for an oral infection.

Generally, it may take one to two weeks for more severe infections before fluconazole reaches its full effect.

Overall, you should begin to feel better during the first few days of treatment with fluconazole.

How Long Does Fluconazole Last in the Body?

It takes about five half-lives to clear from the body after you stop taking fluconazole.

Is It Effective?

Studies have shown that fluconazole is an effective treatment for various yeast infections.

It is also available as an intravenous (IV) solution (injected into a vein).

As such, if you take fluconazole, consistently monitor yourself for emerging side effects.

Call 911 if your symptoms feel life-threatening, or you think you have a medical emergency.

Report Side Effects

Fluconazole may cause other side effects.

Call your healthcare provider if you have unusual problems while taking this medication.

Who Should Not Take Fluconazole?

Fluconazole is not safe for everyone.

This includes those with certain medical conditions like liver, kidney, or heart problems.

While taking fluconazole, do not start any new medications without approval from your healthcare provider.

Some drug interactions include but are not limited to:

This is a partial list of drug interactions.

Other drug interactions may occur with fluconazole.

Consult your healthcare provider for more information about drug interactions and how they may affect you.

You may need to take fluconazole longer to see results for more severe, persistent, or recurring infections.

Ask your healthcare provider regarding what you should expect when taking fluconazole.

Frequently Asked Questions

Store fluconazole at room temperature (between 68 and 77 degrees F).

Keep away from direct light, heat, and moisture.

Keep this medicine out of reach and sight of children and pets.

As a generic, fluconazole is relatively inexpensive and is covered by most prescription plans.

The cost will depend on the dosage and quantity.

DailyMed.Label: Diflucan- fluconazole tablet Diflucan- fluconazole powder, for suspension.

DailyMed.Label: Fluconazole injection.

Boedeker KS, Kilzer WJ.Fluconazole dose recommendation in urinary tract infection.Ann Pharmacother.

2001;35(3):369-372. doi:10.1345/aph.10170

Alkeswani A, Cantrell W, Elewski B.Treatment oftineacapitis.Skin Appendage Disord.

2005;32(1):19-21. doi:10.1111/j.1346-8138.2005.tb00707.x

National Health Service.Common questions about fluconazole.

Brammer KW, Farrow PR, Faulkner JK.Pharmacokinetics and tissue penetration of fluconazole in humans.Rev Infect Dis.

1990;12 Suppl 3:S318-S326.

2004;351:876-883. doi:10.1056/NEJMoa033114

Prescribers' Digital Reference.Diflucan.

U.S. Department of Health and Human Services Office on Womens Health.Vaginal yeast infections.