Peyronie’s diseaseis a condition where the penis becomes curved due to the buildup of fibrous scar tissue.
Historically, surgery has been the most effective form of treatment for Peyronie’s disease.
Surgeries and Specialist-Driven Procedures
In general, Peyronie’s disease isn’t treated until symptoms have stabilized.
Theresa Chiechi / Verywell
That’s because sometimes symptoms can improve on their own.
However, the exception to that rule is when you are in pain.
If your penile curvature is painful, see your healthcare provider sooner rather than later.
There are benefits, and disadvantages, to both surgical options and office-based penile injections.
Intralesional Injections
The only FDA-approved non-surgical therapy for Peyronie’s disease is the Xiaflex injection.
Each cycle takes approximately six weeks to complete with at-home stretching activity between cycles.
An entire treatment course of Xiaflex consists of up to four cycles and takes approximately 24 weeks to complete.
However, concerns about the risks of Xiaflex treatment mean that access is limited.
Therefore, given the risks of radiation, it should not be used.
Surgical Treatments
Surgical treatment for Peyronie’s disease is only appropriate for individuals with stable disease.
Plication:Plicationis the simplest surgery for Peyronie’s disease.
Its use is generally restricted to men who can still attain an erection rigid enough for penetration.
(Whether or not they need medical or vacuum assistance to get an erection.)
Plication involves suturing the penis on the opposite side of the curve for shorten the long side.
This reduces the curvature and may make the penis straight enough for sexual penetration.
However, it can also shorten the length of the penis.
This involves surgical removal or interruption of the plaque that is causing the penis to curve.
It may also involve placing a tissue graft.
The most common types ofpenile prosthesesare inflatable balloons that can help men achieve an erection.
Indeed, this is the only key in of penile prosthesis recommended for Peyronie’s treatment.
Surgical placement of an inflatable prosthesis is often accompanied by other procedures to straighten the penis.
These can include any of the other surgeries described above.
ESWT has not been shown to improve curvature, plaque size, or other symptoms.
This category of drugs can be used for pain relief in people with active disease.
Both ibuprofen and naproxen are types of NSAIDs.
There are no FDA-approved oral remedies for Peyronie’s disease.
There is insufficient evidence that they are actually effective.
One treatment for which there is mild evidence is penile traction devices.
These devices are used to gently straighten the penis.
Hand molding may be done at home.
It involves gentle reshaping of the penis, as taught by a healthcare provider.
It is not generally considered to be a home remedy, rather it is an adjunct to other treatment.
Sexual intimacy can be an important part of many people’s lives.
For many men, sexual penetration feels like a critical component of intimacy.
However, many individuals have satisfying, fulfilling sex lives without engaging in penetrative sex.
Done correctly,stretchingcan alter penile tissue and successfully lengthen and correct curvature related to Peyronies disease.
Levine LA, Larsen SM.Surgery for Peyronie’s disease.Asian J Androl.
2010;34(5):444-9.
A controlled study of 70 cases.Andrology.
