If none of these treatments is an option, palliative care may be necessary.
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Surgeries and Specialist-Driven Procedures
Liver metastasis requires immediate attention.
Advances in imaging and surgical techniques, such as laparoscopy and robotics, have made this option increasingly available.
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Many factors must be considered regarding the safety and feasibility of resection.
For instance, a substantial portion of healthy functioning liver must be available to remain after surgery.
Chemotherapy
Chemotherapyis the use of medications to destroy, shrink, or inhibit cancer cells.
Most chemotherapy drugs are delivered intravenouslydirectly into a vein.
The specific chemotherapy drug used to treat secondary liver cancer will depend on the site of the primary tumor.
The punch in of chemotherapeutic drugs used most often for liver metastasis that originated in the colon are fluoropyrimidines.
By taking up the drug instead of actual nourishment, the cancer cells eventually die.
HAI has fewer potential side effects than standard chemotherapy and may improve survival rates.
Biologics typically are delivered intravenously or through an implanted vascular access equipment.
They may be given in conjunction with chemotherapeutic drugs.
There are several types of biologics used to treat liver metastasis coming from colon cancer.
Therefore, oncologists routinely test for this mutation.
A mutation of KRAS may be present in different types of cancer (colorectal, pancreas,lung).
Ablation
Ablation is the non-surgical removal or destruction of cancerous tissue.
The objective is to leave as much healthy liver tissue intact as possible.
It generally has been believed that a transplant is not feasible in cases of secondary liver cancer.
It can be used at any time during treatment for secondary liver cancer.
Other procedures, such paracentesis or abdominal tap, may be used to to drain fluid from the abdomen.
It involves a team comprised of doctors, nurses, home care workers, and other supportive personnel.
Secondary liver cancer is regarded as stage 4 cancer, which means it’s advanced and rarely curable.
Oncologists have tools for treating this disease that can dramatically improve quality of life and even extend it.
Mitchell D, Puckett Y, Nguyen QN.Literature Review of Current Management of Colorectal Liver Metastasis.Cureus.
2019:1-6. doi:10.1007/978-3-030-25486-5_1
Chow FC, Chok KS.Colorectal liver metastases: An update on multidisciplinary approach.World J Hepatol.
J Gastrointestin Liver Dis.
2012;21(1):83-91.
Li Y, Martin RC.Herbal medicine and hepatocellular carcinoma: applications and challenges.Evid Based Complement Alternat Med.
20 Feb 2011;2011:541209. doi:10.1200/JOP.2015.009407
Mcdermott S, Gervais DA.Radiofrequency ablation of liver tumors.Semin Intervent Radiol.
2010;17 Suppl 1:S31-40.
