Get our printable guide for your next doctor’s appointment to help you ask the right questions.

Researchers still do not fully understand how beta-blockers work for migraine prevention.

Anticonvulsants

Also sometimes referred to as membrane stabilizers, these medications are primarily prescribed to prevent seizures.

Young man taking pills for a headache

Antonio_Diaz / Getty Images

With instruction, most people are able to learn to give themselves the shots.

Vyepti is given intravenously (IV), while Nurtec ODT and Qulipta are taken in pill form.

Botox (also called Onabotulinum-A) is a diluted form of a bacterial toxin that paralyzes muscles.

Doctor Discussion Guide Old Woman

Get our printable guide for your next doctor’s appointment to help you ask the right questions.

This prompted researchers to studyBotox injectionsas a preventive treatment for migraines.

It was found to be effective only for chronic migraines, a use that the FDA ultimately approved.

It can take up to six months to get the full therapeutic effects.

As such, opting for an FDA-approved migraine drug is usually preferred.

Using a drug off-label may be effective and perfectly safe for you.

A Word From Verywell

Prophylaxis is a vital part of migraine management.

Ha H, Gonzalez A.Migraine headache prophylaxis.Am Fam Physician.

2019;99(1):17-24.

American Migraine Foundation.Prevention of migraine.

2012;4:37-49. doi:10.4137%2FJCNSD.S9049

American Migraine Foundation.Botox for migraine.

U.S. Food & Drug Administration.Consumer updates: Is it really FDA approved?

Marmura MJ, Kumpinsky AS.Refining the benefit/risk profile of anti-epileptic drugs in headache disorders.CNS Drugs.

2018;32(8):735-746. doi:10.1007/s40263-018-0555-z

Rapoport, AM.How to choose a preventive medication for migraine.

Information for Health Care Professionals.

The American Headache Society.