However, experts warn that the therapy may not be effective and could be unsafe.
Does ExtenZe Help With Erectile Dysfunction?
No clinical studies support the use of ExtenZe for erectile dysfunction.
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Some of the ingredients in ExtenZe have been studied separately; however, studies on humans are lacking.
These studies are small and do not properly check for safety and toxicity.
ExtenZe claims that you will see an increase in erection size when using this product.
There is no research or scientific evidence to support this.
How Long Does It Take to Work?
It advises that it should be taken for eight weeks to see the greatest benefit.
It offers a money-back guarantee for up to 67 days after purchase.
No clinical studies have tested the effectiveness of ExtenZe or how quickly it works.
How long it will take to work or whether it works at all remains unknown.
There are no studies of its effects on erectile dysfunction.
It is thought to have a vasodilating effect.
Dehydroepiandrosterone
Dehydroepiandrosterone (DHEA)is a steroid hormone that is produced in the adrenal glands.
The body converts DHEA to estrogen and testosterone.
Folic Acid
Folic acid, or vitamin B9, is necessary to make healthy red blood cells.
Horny Goat Weed
Horny goat weedis used in Traditional Chinese Medicine as an aphrodisiac.
It is from the plantEpimediumand contains the active ingredient icariin.
L-Arginine Hydrochloride
Two studies have shown positive results for ED with daily high-dose L-arginine supplementation.
Participants reported improved penile erectile function after oneto three monthsof use.
Maca
Maca is a root vegetable grown in Peru.
It is also known asLepidium meyenii.
A study from 2020 showed that after 12 weeks of use, Maca can increase sperm concentration.
Another study from 2023 showed that erectile function scores increased after 12 weeks in men with hypogonadism.
Studies involving muira puama for men with ED are lacking.
After three months, people who took this supplement reported improvements in their sexual function scores.
Niacin
Niacin, or vitamin B3, is an essential nutrient.
An observational study found that a higher dietary intake of niacin was associated with a lower risk of ED.
Niacin is thought to help ED by improving vascular endothelial function and reducing oxidative stress.
There is currently no research on the benefits of pregnenolone for ED.
Tribulus Terrestris
Tribulus terrestrisis an herbal plant used in Traditional Chinese Medicine and Ayurvedic medicine.
Velvet Bean Extract
Velvet bean, orMucuna pruriens, is a legume used in Ayurvedic Indian medicine.
This can increase blood flow to the penis which helps to enable erections.
It has been used as an aphrodisiac in African countries.
Zinc
Zincdeficiency has been associated with lower levels of testosterone and lower levels of sperm in semen.
Studies on the effectiveness of zinc in people with ED are lacking.
Is It Safe to Take?
Extenze is considered a dietary supplement.
Dietary supplements do not follow the same regulations as prescription medications.
Supplements are not approved by the US Food and Drug Administration (FDA) for safety or effectiveness.
Certified GMP facilities have been tested and follow proper regulations.
Supplements may even contain hidden ingredients.
In 2018, the FDA warned the public not to purchase ExtenZe Plus.
It was found to contain an active ingredient, sildenafil, which is a prescription product for erectile dysfunction.
It is also the active ingredient in Viagra.
The FDA has placed ExtenZe on its list of tainted sexual enhancement products and recommends avoiding this supplement.
Who Should Avoid ExtenZe
ExtenZe has previously proved to contain sildenafil.
Sildenafil and other PDE5 inhibitors can lower blood pressure.
The safety and side effects of the ingredients in ExtenZe have not been studied in clinical trials.
Additionally, no studies have been conducted to demonstrate how well ExtenZe works for supporting ED.
They cause blood vessels to relax, which increases blood flow to the penis.
When the penis is sexually stimulated, an erection will occur.
Supplements have less stringent regulations and are not FDA-approved.
Male enhancement supplements have been found to contain unlisted ingredients and have caused severe side effects.
They can direct you toward effective and safe medications to treat your condition.
National Institute of Diabetes and Digestive and Kidney Diseases.Definition and facts for erectile dysfunction.
International Business Times.Maker of penis-enlargement pill ‘ExtenZe’ forced to settle lawsuit.
National Center for Complementary and Integrative Health.Astragalus.
Li H, Jiang H, Liu J.Traditional Chinese medical therapy for erectile dysfunction.Translational Andrology and Urology.
2017;6(2):192-198. doi: 10.21037/tau.2017.03.02
Examine.DHEA.
2020;141:111110. doi:https://doi.org/10.1016/j.exger.2020.111110.
2013;98(9):3615-3626. doi:10.1210/jc.2013-1358
U.S. Anti-Doping Agency.What should athletes know about DHEA?
JNFS 2017; 2 (2) :165-172. fruit.Journal of Acupuncture and Meridian Studies.
2011;4(2):134-140. doi:https://doi.org/10.1016/s2005-2901(11)60020-4.
National Academies of Sciences.Reproductive steroid hormones: synthesis, structure, and biochemistry.
National Academies Press (US); 2020.
2019;5(10):e02716.
2021;320:110705. doi:https://doi.org/10.1016/j.forsciint.2021.110705.
2009;2(2):57-61. doi:10.4103/0974-1208.57223
U.S. Food and Drug Administration.Information for consumers on using dietary supplements.
U.S. Food and Drug Administration.Current good manufacturing practices (CGMPs) for food and dietary supplements.
U.S. Food and Drug Administration.Public Notification: ExtenZe Plus contains hidden drug ingredient.
National Center for Complementary and Integrative Health.Yohimbe.
Myers A, Barrueto F.Refractory priapism associated with ingestion of yohimbe extract.Journal of Medical Toxicology.
2009;5(4):223-225. doi:10.1007/bf03178272
U.S. Food and Drug Administration.Tainted sexual enhancement and energy products.
UpToDate.Sildenafil: drug information.
UpToDate.Treatment of male sexual dysfunction.
National Institute of Diabetes and Digestive and Kidney Diseases.Treatment for erectile dysfunction.