MS patients may experience symptoms that fluctuate, with some worse at night and others worse during the day.

For example, musclespasmsand stiffness tend to get worse at night, while heat-related symptoms worsen during the day.

Learn more about symptoms of MS, how they shift from day to night, and more.

Person with multiple sclerosis and support dog

Mark Hunt / Getty Images

Mark Hunt / Getty Images

Do MS Symptoms Fluctuate Throughout the Day?

There is no standard set ofMS symptomsthat people with the disease experience during the day and at night.

Everyone experiences symptoms differently, and specific symptoms can change over time.

Differentlifestyle behaviorsduring the day and night can also make symptoms seem better or worse.

For example, if the pain worsens in the afternoon, pain medications can be taken before that time.

These symptoms can fluctuate depending on the time of day.

There are things people with MS can do to cope with symptoms during day and night time fluctuations.

For example, if pain increases at night, medications can be taken before that time.

A Word From Verywell

Living with MS and symptoms that change can be confusing and challenging.

If you or someone you know is facing MS and fluctuating symptoms, help is available.

Reach out to a healthcare professional for support.

MS spasticity may feel different for different people.

In general, it feels like extremely stiff, tight muscles.

People with MS spasticity may also experience muscle spasms.

Symptoms of MS can be better or worse at different times of the day.

For example, spasticity can worsen at night, while fatigue can worsen during the day and after activities.

However, this is unique to each person.

Johns Hopkins Medicine.Multiple sclerosis (MS).

MS Society.Understanding spasms and stiffness.

National Multiple Sclerosis Society.MS signs and symptoms.

National Multiple Sclerosis Society.Fatigue.

2013;19(7):932-940. doi:10.1177/1352458512463765

Sleep Foundation.Multiple sclerosis (MS) and sleep.

Murphy KL, Bethea JR, Fischer R.Neuropathic pain in multiple sclerosiscurrent therapeutic intervention and future treatment perspectives.

In: Zagon IS, McLaughlin PJ, eds.Multiple Sclerosis: Perspectives in Treatment and Pathogenesis.

Peyronnet B, Krupp LB, Reynolds WS, et al.Nocturia in patients with multiple sclerosis.Rev Urol.

2019;21(2-3):63-73.

Multiple Sclerosis Association of America.Anxiety in MS: frequently overlooked and undetected.

Multiple Sclerosis Association of America.Visual disorders.

Multiple Sclerosis Trust.Diary of symptoms.

2019;27:419-423. doi:10.1016/j.msard.2018.11.013

Rogers KA, MacDonald M.Therapeutic yoga: symptom management for multiple sclerosis.J Altern Complement Med.

2015;21(11):655-659. doi:10.1089/acm.2015.0015