In these cases, healthcare providers need to methodically exclude all other causes before a diagnosis can be made.

This process is calleddifferential diagnosis.

Thyroid disease can be diagnosed by performing blood tests to evaluate the T3 and T4 levels.

Doctor and patient talking in exam room

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Further tests would be performed to pinpoint the underlying cause.

PCOS can similarly trigger increases in prolactin levels.

One of the more common causes of hyperprolactinemia is a pituitary tumor called a prolactinoma.

A prolactinoma can either be large or small and is most often benign (noncancerous).

Hyperprolactinemia also requires a differential diagnosis to exclude thyroid disease as a cause.

A magnetic resonance imaging (MRI) test can be used to confirm the presence of a tumor.

Unlike PCOS, CAH can be diagnosed with a genetic test.

Cushing’s Syndrome

Cushing’s syndrome is a disease that causes the overproduction of adrenal hormones.

As with PCOS, there is no single test to confirm a Cushing’s diagnosis.

“Amer Fam Phys.2016; 94(2):106-13.