Cushing’s syndromeis an endocrine disorder caused when the adrenal glands produce excess cortisol.
Also known as hypercortisolism, Cushing’s syndrome can occur for various reasons.
One of the most common causes is long-term exposure to corticosteroid medications like prednisone.
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Cushing’s syndrome that’s resulting from steroids is called iatrogenic (or exogenous) Cushing’s syndrome.
Given cortisol’s benefits, this doesn’t seem like a bad thing.
In general, healthcare providers will work toward getting patients weaned off steroid drugs such asprednisoneas soon as possible.
While steroid medications are extremely effective, they can have profound effects, including the development of Cushing’s.
The judicious use of steroids might be warranted in some cases.
However, it is a treatment choice that should be discussed carefully.
Treatment Options
Cushing’s syndrome is treated by lowering the levels of cortisol in the body.
Any changes to your steroid use must be done under a healthcare provider’s supervision.
Stopping the drug suddenly can have serious effects on the body.
Patients can also take some steps at home to treat the effects of Cushing’s syndrome.
It’s important to work closely with your medical team and report any side effects you may be experiencing.
The goal is always to get patients off steroids as quickly and as safely as possible.
Nieman LK.Diagnosis of Cushing’s Syndrome in the Modern Era.Endocrinol Metab Clin North Am.
2014;43(1):75102. doi:10.1016/j.ecl.2013.10.005
Pacifici R.The immune system and bone.Arch Biochem Biophys.
2010;503(1):4153. doi:10.1016/j.abb.2010.05.027
National Institute of Diabetes and Digestive and Kidney Diseases.Cushing’s Syndrome.
