HCM is generally inherited in anautosomal dominantmanner.
This article discusses HCM and its causes, including genetics and risk factors for complications.
Adding to the complexity, however, is the fact that several different types of mutations exist.
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Sarcomeresare proteins found in muscle cells.
They are found in about 70% of cases.
The other sarcomere mutations each account for only 1%5% of HCM mutations.
Genetic testing is performed in people whose imaging tests reveal signs of HCM.
It is particularly useful after adiagnosis of HCMto test family members for the gene mutation.
Mutations in sarcomeres, which make up heart muscle fibers, are responsible for most HCM cases.
These are known as “variants of uncertain significance.”
As our understanding of genetics in HCM evolves, these variants may be further clarified.
These devices monitor the heart rhythm and provide a shock of electricity to stop dangerous arrhythmias.
The following are factors found to be associated with increased risk of SCD.
Findings on Heart Rhythm Monitoring
People with HCM undergo heart rhythm monitoring to evaluate for arrhythmias.
Treating HCM
Fortunately, there are many effective and promisingtreatments for HCM.
Having a genetic mutation increases risk, but does not mean that your heart will necessarily be severely affected.
Genetic testing is particularly useful for evaluating family members.
Cardiac testing will help you and your healthcare provider determine a treatment and follow-up plan.
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