They also have a 13% greater risk of heart failure.

Heres what experts want you to know about protecting your joints and heart if you have carpal tunnel syndrome.

When it is deposited into heart muscle, it can lead to cardiac amyloidosis, said Majure.

Close-up of woman sitting at desk holding her hand in pain

andreswd / Getty Images

People may have symptoms like shortness of breath, fatigue, and fluid retention.

In serious cases, it can lead to an early death.

Who Gets Carpel Tunnel and Stiff Heart Syndrome?

The misfolding leads to the formation of amyloid deposits in various tissues, including the heart.

Over time, the deposits can affect heart function, potentially leading to cardiac amyloidosis.

Should You Worry About Your Heart If You Have Carpel Tunnel?

Providers may consider a proactive approach by discussing cardiac screening when appropriate.

Can You Be Tested for Stiff Heart Syndrome?

Screening for underlying conditions like TTR-related amyloidosis may be considered in specific cases, said Chaparro.

Amyloidosis can lead to heart disease, but there are treatments available when its diagnosed early, said Majure.

Your provider may ask you questions about your family history to determine if additional testing is needed.

2024;99(7):1101-1111. doi:10.1016/j.mayocp.2023.11.016

National Institute of Arthritis and Musculoskeletal and Skin Diseases.Carpal tunnel syndrome.

Penn Medicine.What is cardiac amyloidosis?.

American Medical Association.What doctors wish patients knew about carpal tunnel syndrome.

National Library of Medicine: MedlinePlus.Carpal tunnel syndrome.

National Library of Medicine: MedlinePlus.TTR gene.

American Heart Association.Genetic testing and counseling for hereditary transthyretin amyloidosis (hATTR).