Usually, healthcare providers attempt to limitpolypharmacy, or your exposure to excess or redundant medications.
But does this guidance apply to over-the-counter pain medications, too?
However, their combined use can sometimes reduce pain enough that you don’t need stronger opioid medications.
Verywell / Jessica Olah
It is often combined with other medications.
Althoughthe exact mechanism of Tylenolremains unclear, we believe this medication works by inhibiting cyclo-oxygenase (primarily COX-2).
Long-term use of Tylenol should only occur if prescribed by a healthcare provider.
About Motrin
Motrin (ibuprofen) is anNSAID(nonsteroidal anti-inflammatory drug).
Like Tylenol, it exerts its effects on cyclo-oxygenase and inhibits prostaglandin synthesis.
Prostaglandins mediate pain, inflammation, and fever.
Inhibition in prostaglandin synthesis also results in vasoconstriction and renal impairment which can lead to kidney failure.
Thus, people with kidney problems should steer clear of Motrin.
NSAIDs also should only be used if prescribed by a healthcare provider.
Some of the earliest research was conducted among children.
Opioids are prescription medications that have serious long-term side effects and a high potential for dependence and abuse.
Many of these contain acetaminophen or an NSAID for added pain relief.
It is also important to remember that Tylenol or Motrin are only intended for short-term use.
If your pain persists, call your healthcare provider.
National Institute on Aging.The dangers of polypharmacy and the case for deprescribing in older adults.
Food and Drug Administration.Drug interactions: what you should know.
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MyHealth.Alberta.ca.Substance use: common drugs.
