It is a first-generation antihistamine with side effects such as drowsiness, slowed breathing, and sleepiness.
As a central nervous system (CNS) depressant, alcohol can worsen the side effects of Benadryl.
What Happens When You Mix Alcohol and Benadryl?
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These include:
Is Any Amount of Alcohol Safe?
Does Alcohol Interact With All Antihistamines?
Avoid taking alcohol with all antihistamines.
However, they can still cause side effects when taken with alcohol.
Who Is at Higher Risk?
In some cases, people are more at risk when using Benadryl.
If you are taking any prescription or OTC drugs, ask your healthcare provider.
Taking these drugs together enhances the effect of Benadryl.
It is a potent first-generation antihistamine that can cause drowsiness.
Taking alcohol with Benadryl can increase the sedating effect and drowsiness and even lead to the danger of overdosing.
When taking Benadryl, avoid using other products containing diphenhydramine as well, as it can be life-threatening.
Always ask your healthcare provider what not to take with Benadryl before taking this medicine.
MedlinePlus.Diphenhydramine
National Cancer Institute.Blood-brain barrier.
Medical Society of the State of New York.#34 Alcohol content in common preparations.
Dailymed.Label: Benadryl allergy extra strength- diphenhydramine hydrochloride tablet, film-coated
PDR.Benadryl.