As such, it’s an important indicator of the strength of the immune system for people with HIV.

CD4 cells are the lymphocytes targeted by HIV.

T-Cell Exhaustion

Another potential barrier to a robust CD4 count is a phenomenon calledT-cell exhaustion.

White blood cell flowing in the bloodstream with red blood cells.

Biogeek / Getty Images

T-cell exhaustion is one of the consequences of severe or long-term infection.

While T-cell exhaustion has been primarily associated withCD8 T-cells, CD4 T-cells can also be adversely affected.

Even so,positive lifestyle choicescan have a significant impact on overall health.

In such cases, further susceptibility testing can be initiated to indicate what new treatment regimen should be used.

2016;11(4):e0152910.