There is currently no cureforpsoriatic arthritis(PsA).

Psoriatic arthritis is a throw in of inflammatory arthritis affecting people withpsoriasis, an inflammatory skin condition.

Psoriasis speeds up skin cell growth, causing them to build on the surface of the skin.

female physician looking at medications on shelf

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Symptoms of PsA include joint pain, stiffness, and swelling, along with skin lesions associated with psoriasis.

The goal of PsA treatment is to improve skin and joint symptoms.

There are many medicinal options for treatment that may include one or more of the following drug therapies.

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Get our printable guide for your next doctor’s appointment to help you ask the right questions.

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NSAIDs are effective for people whose PsA is mild.

However, recent studies have shown no difference in stomach side effects between NSAIDs and COX-2 inhibitors.

Too much TNF leads to inflammation.

Biologic DMARDs are expensive, so doctors wont prescribe them unless other medications have not helped to improve symptoms.

Moreover, like biologics, they must undergo strict Food and Drug Administration (FDA) testing.

JAK is a cytokine (chemical messenger) that researchers believe plays a role in causing inflammation.

Target-specific DMARDs are not a first-line therapy for PsA.

In doing so, they can reduce inflammation in the body.

Corticosteroid is generally injected into affected joints.

A Word From Verywell

Your doctor can determine what medicationor medicationsare right for your unique situation.

Benjamin O, Goyal A, Lappin SL.Disease-modifying antirheumatic drugs (DMARD)[Updated 2023 Jul 3].

In: StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing.

2017; 9: 2128.doi: 10.2147/OARRR.S56073

National Psoriasis Foundation.Biologics.

2013 Apr;72 Suppl 2(0 2):ii111-5.

doi:10.1136/annrheumdis-2012-202576

Ruderman EM.Overview of safety of non-biologic and biologic DMARDs.Rheumatology (Oxford).

2012;51(Suppl 6):vi37-43.

doi:10.1093/rheumatology/kes283

U.S. Food & Drug Administration.Biosimilars.