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Vitamin B6 (pyridoxine) is one of eight B vitamins.

Skin Changes

Vitamin B6 deficiency can contribute to skin changes such as:

2.

Tiredness and Brain Fog

Vitamin B6 helps convert food into fuel for energy.

A person working at a laptop feels fatigue

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Symptoms of severely low B6 may include:

5.

Weakened Immune System

Vitamin B6 helps the body make immune system cells and proteins.

Anemia

You need vitamin B6 to form the oxygen-carrying protein hemoglobin in red blood cells.

Symptoms of anemia can include:

7.

Seizures

A severe vitamin B6 deficiency can disrupt electrical activity in the brain.

In some cases, this can cause epilepticseizures.

Vitamin B6 is a water-soluble vitamin, which means excess B6 leaves the body in urine.

Because the body doesn’t store it, foods containing B6 should be part of your regular diet.

Eating a balanced, healthy diet with a variety of foods is recommended to prevent deficiency.

You’ll also find B6 in many multivitamins or B-complex vitamins.

Blood and urine testing can also help determine levels of B vitamins.

No special preparations are necessary.

These symptoms can also be due to other conditions.

Summary

Symptoms of vitamin B6 deficiency include fatigue, swollen tongue, and skin changes.

A severe deficiency can lead to anemia or a weakened immune system.

The body doesn’t store vitamin B6.

Even so, B6 deficiency is uncommon.

it’s possible for you to get B6 from a variety of foods and dietary supplements.

See a healthcare provider if you think you havevitamin deficiencies.

In most cases, dietary changes or vitamin B6 supplements may be all you need.

Merck Manual.Vitamin B6 deficiency.

National Institutes of Health Office of Dietary Supplements.Vitamin B6: fact sheet for health professionals.

Yasuda H, Hoshino Y, Ando J, et al.Vitamin B6 deficiency polyneuropathy and dermatitis.Am J Med.

2023;136(1):e10-e11.

Penn Medicine.6 signs you have a weakened immune system.

National Heart, Lung, and Blood Institute.Anemia: symptoms.

Merck Manual.Vitamin B6 deficiency and dependency.

2016;316(13):1392-401. doi:10.1001/jama.2016.14337

Harvard T.H.

Chan School of Public Health.Vitamin B6.