Morning sickness can be managed with lifestyle changes such as diet, herbal supplements, and rest.
However, many over-the-counter (OTC) products and prescription medications are available for morning sickness, too.
Which medication you take may depend on the severity of your symptoms.
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However, its mechanism of action (how it works) for controllingpregnancy nauseais unknown.
However, you should always consult your healthcare provider before starting a supplement to ensure it’s safe.
Common side effects of vitamin B6 supplementation may include:
2.
Activation of these receptors can trigger signals that cause nausea and vomiting.
Doxylamine is found in many OTC sleep aids.
you’re free to take it along with vitamin B6 to help relieve morning sickness.
It can be purchased as a generic or brand-name product, such as Unisom.
However, it’s important to read the medicine’s label first.
Some Unisom products, such as Unisom SleepGels Nighttime Sleep-Aid, contain a different active ingredient called diphenhydramine.
The ACOG recommends adding doxylamine when vitamin B6 alone does not relieve symptoms.
There is also a prescription formulation that combines the two in one pill.
Pyridoxine-Doxylamine Combination Pill
A prescription medication containing pyridoxine and doxylamine in one pill is also available.
This medicine is usually used when non-drug treatments and OTC options are ineffective at treating your nausea and vomiting.
Dopamine Agonists
Dopamine antagonists include antipsychotics and antiemetics.
Antiemetic drugs are used to treat nausea and vomiting in pregnancy.
They may be combined with other treatments, such as antihistamines and vitamin B6.
These medications may be considered if other treatments are ineffective for mild or moderate symptoms.
These drugs are not associated with an increased incidence ofcongenital disorders(abnormalities or conditions present at birth).
Serotonin antagonists include:
These medications are available as oral pills and injections.
Ondansetron is a common serotonin antagonist prescribed to prevent or treat morning sickness.
This could mean combining medications with some dietary changes.
Summary
Morning sickness can be an uncomfortable condition for pregnant people.
However, in certain cases, you may need to try medications.
OTC products commonly include vitamin B6, antihistamines, and other combination products.
2023;308(4):1075-1084. doi:10.1007/s00404-023-06925-w
National Institutes of Health Office of Dietary Supplements.Vitamin B6.
2016;316(13):1392-1401. doi:10.1001/jama.2016.14337
Herrell HE.Nausea and vomiting of pregnancy.Am Fam Physician.
2014;89(12):965-970.
DailyMed.Label: Bonjesta- doxylamine succinate and pyridoxine hydrochloride tablet, extended release.
DailyMed.Label: Diclegis- doxylamine succinate and pyridoxine hydrochloride tablet, delayed release.
2023;14:1291235. doi:10.3389/fphar.2023.1291235
Ondansetron (Zofran).
In:Mother To Baby | Fact Sheets.
Organization of Teratology Information Specialists (OTIS);1994.
DailyMed.Label: Ondansetron tablet, film coated.
UpToDate.Patient education: nausea and vomiting of pregnancy (beyond the basics).
